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Brunner (Johann Conrad). Experimenta nova circa pancreas, accedit diatribe de lympha & genuino pancreatis usu, 1st edition, Amsterdam: Henr. Wetstenius, 1683, four engraved plates including two folding (the last with two closed tear repairs to verso), lacks additional engraved title, library stamp to title and plates, running wormhole to lower margins of first two quires not affecting text, library cloth, 8vo. Brunner came near to discovering pancreatic diabetes. His experiments on the dog represent pioneer work on internal secretion. Following excision of the pancreas, he recorded extreme thirst and polyuria` (G-M 3927); Norman 362; Waller 1566; Wellcome II, 258. (1)

Bullein (William). Bulleins Bulwarke of Defence Against all Sicknesse, Soarnesse, and Woundes that doe Dayly Assaulte Mankinde: Which Bulwarke is Kept with Hilarius the Gardener & Health the Phisicion, with the Chirurgian, to Helpe the Wounded Souldiours. Gathered and Practised from the Most Worthy Learned, both Olde and New: to the Great Comfort of Mankinde, 4 parts in one, 3rd edition, Thomas Marshe, 1579, titles within woodcut border (first title trimmed to top and outer margins affecting borders), woodcut arms of the Order of the Garter to first title verso, woodcut illustrations and historiated initials, text in black letter, lacking rear blank 3F6, occasional annotations and light marginal water stains, one or two lower corners torn away, P2 rehinged, a few leaves trimmed at aouter margin, previous owner names of Guilielimus Reade and Otwell Worsley (dated 24 August 1621) to first title, library cloth, folio (281 x 185mm) The first part The Booke of Simples` is of interest as being one of the earliest herbals in English. William Bullein (c. 1520-1576) was a Tudor physician and possible kinsman to Anne Boleyn, and the book is a mixture of medical advice, herbal remedies and forthright political comment, sprinkled with jokes and puns. Durling 779; STC 4034; Wellcome I, 1149. (1)

Bunon (Robert). Essay sur les maladies des dents ..., 1st edition, Paris, 1743, 3 pp. approbation at rear, library stamp to title, old dampstaining to lower and outer margins, modern morocco gilt over marbled boards, 12mo (164 x 94mm) G-M 3672.1. The Essay was the first of Bunon`s important works on dentistry and one of the first books devoted to children`s teeth, being published just one year after Hurlock`s great work (see lot 216). (1)

Burton (John). An Essay Towards a Complete New System of Midwifery, Theoretical and Practical. Together with the Descriptions, Causes and Methods of Removing, or Relieving the Disorders Peculiar to Pregnant and Lying-in Women, and New-born Infants... in four parts, 1st edition, 1751, eighteen etched plates (17 folding) by George Stubbs, a few strengthened along folds to verso) light toning and offsetting, previous owner signature erased from title (with surface abrasion), library stamps, BMI presentation label from Dr Smallwood Savage, modern calf-backed boards, 8vo, together with A Letter to William Smellie, M.D. Containing Critical and Practical Remarks upon his Treatise on the Theory and Practice of Midwifery. Wherein the Various Gross Mistakes and Dangerous Methods of Practice Mentioned and Recommended by that Writer, are Fully Demonstrated and Generally Corrected, by John Burton, 1st edition, 1753, folding engraved plate, errata leaf at end, occasional light spotting and browning, previous owner signature of John Freer to title and front endpaper, his bookplate to front pastedown, modern calf-backed boards, 8vo. Burton was the first to suggest that puerperal fever is contagious, and the first to give a detailed discussion of Caesarean section` (G-M 6268). The plates are the earliest published engravings by George Stubbs and his first attempt at etching (he prepared for the illustrations by dissecting a female cadaver he had secretly kept in an attic). Burton`s rival, the eminent London man-midwife William Smellie, had published his warmly received Treatise on the Theory and Practice of Midwifery in 1751, with Burton reacting with his critical Letter to William Smellie above. Burton was satirized as `Dr. Slop` in Laurence Sterne`s Tristam Shandy, following political differences with York clergyman Dr Jacques Sterne (Laurence`s uncle and prominent Whig) and accused of treason during the Jacobite Rising of 1745. G-M 6268; Norman 380; Waller 1667. (2)

Castro (Rodrigo de). De universa muliebrium morborum medicina, novo & antehac nemine tentato ordine opus absolutissimum; et Studiosis omnibus utile, Medicis vero pernecessarium, 4th enlarged and corrected edition, 2 parts in one volume, Hamburg: Zacharias Hertel, 1662, first title in red & black with allegorical engraving, separate title and register to second part, folding table, library stamp to title and table, bound with Medicus-politicus: sive de officiis medico-politicis tractatus, Hamburg: Zacharias Hertel, 1662, final blank present, occasional browning to both works, contemporary vellum, soiled, 4to. The Portuguese Jewish physician Rodrigo de Castro (1546-1627) fled from the Inquisition to become one of the earliest Jewish settlers in Hamburg. The first work here is his influential work on gynaecology: Krivatsy 2289; Wellcome II, p 312. The second work is one of the first `modern` works on medical ethics. It includes chapters on problems in forensic medicine, e.g. the examination of injuries, virginity, impotence, signs of poisoning and the examination of slaves` (Norman 416); G-M 1759; Krivatsy 2291; Waller 1821 (all citing the first edition of 1614). (1)

Charleton (Walter). Enquiries into Human Nature, in VI. Anatomic Praelections in the New Theatre of the Royal Colledge of Physicians in London, 1st edition, Robert Boulter, 1680, imprimatur leaf before title, engraved portrait frontispiece cut down and relaid, engraved plate of the Cutlerian Theatre following title, six engraved illustrations to text (Of Motion Voluntary), 4 pp. publisher`s ads at rear, faint library stamp to portrait lower corner and title, hinges slightly cracked, library cloth, short split to upper joint, 4to, together with De scorbuto liber singularis, Guliel Wells & Rob. Scott, 1672, library stamp to title, some old water staining throughout, lacks initial and final blank, library cloth, 8vo. These were the first lectures given in the Cutlerian Theatre of the Royal College of Physicians, delivered by Walter Charleton (1619-1707) while he was president (1689-1691). Krivatsy 2390; Osler 2296; Wellcome II, 329; Wing C3678 & Wing C3669. (2)

Cheselden (William). Osteographia, Or the Anatomy of the Bones, 1st edition, 1733, engraved frontispiece, title with engraved vignette, engraved royal arms on separate sheet, engraved dedication, (with deer skeleton to verso), 29 engraved illustrations, 112 engraved plates (complete), comprising two sets of plates numbered I-LVI by Jacob Schijnvoet and Gerard van der Gucht, first set lettered with explanatory text to verso, second set unlettered and without text, plate LVI of first set with deer skeleton to verso; plate LVI of the second set with obelisk ruin in red, historiated initials, occasional light spotting and toning, endpapers renewed, hinges reinforced, contemporary half calf, rebacked, corners chipped, folio. The most famous and among the most artistically interesting osteological atlases ever produced` (Norman), the first full and accurate description of human skeletal anatomy. One of only 400 copies, `which being finished, the plates shall be destroyed that the price of the book may never sink in the possession of the subscribers` (from To the Reader`). The accuracy of the drawing of the large plates of bones is derived from Cheselden`s innovative use of the camera obscura (the use of which is depicted on the title vignette and used for the first time solely for book illustration). The thick paper and large folio format allowed for life-size illustrations of separate human bones. William Cheselden (1688-1752) studied anatomy under William Cowper (1666-1709), becoming full surgeon at St Thomas`s Hospital in 1720. A pioneer of surgical techniques in bladder stone removal and ophthalmics, he is credited with performing the first known successful case of restorative eye surgery on a blind 13-year-old boy, an iridotomy, using a cataract-extraction knife to create an artificial pupil. G-M 395; Norman 466; Waller 1941. (1)

Chisholm (Colin). An Essay on the Malignant Pestilential Fever introduced into the West Indian Islands from Boullam, on the Coast of Guinea, as it appeared in 1793 and 1794, 1st edition, 1795, library stamp to title, untrimmed, modern library half morocco, 8vo, together with Butter (William), A Treatise on the Kinkcough, 1st edition, 1773, browning to first and last few leaves, contemporary calf, later reback, 8vo, and Blackmore (Richard), A Treatise of Consumptions and other Distempers belonging to the Breast and Lungs, 2nd edition, 1725, faint library stamp to title, contemporary calf, modern reback, 8vo, and Fearon (Henry), A Treatise on Cancers, 3rd edition, 1790, half-title, owner`s name excised to upper margin of title, bound with Pearson (John), Practical Observations on Cancerous Complaints, 1793, library cloth, 8vo, together with Bennet (Christopher), Tabidorum Theatrum, Leiden: Coster, 1714, title in red and black, four engraved plates, library cloth, small 8vo, plus two other related works including a 5th edition of Deidier`s Traite des Tumeurs` (1732), and Deshaies Gendron`s Enquiries into the Nature, Knowledge, and Cure of Cancers` (1701), plus five others on fevers (12)

Cole (William). A Physico-Medical Essay Concerning the Late Frequency of Apoplexies, together with a General Method of their Prevention, and Cure, in a Letter to a Physitian, 1st edition, Oxford: printed at the [Sheldonian] Theater, 1689, imprimatur leaf and engraved portrait frontispiece before title (with printer`s vignette device), library stamp to portrait and title, old ink inscriptions to title, the monogram W P` repeated and Bib. Harv. C.S.`, bound with Purcell (John), A Treatise of Vapours, or Hysterick Fits... , 1st edition, printed for Nicholas Cox, 1702, lacks L8 (blank) before index, some spotting, library stamp and early ownership signature of Andrew Hall to title, library cloth, slightly rubbed and soiled, 8vo, (169 x 106mm) 1) Krivatsy 2569; Wing C5043. 2) Hunter & Macalpine, pp. 288-291. Both works are rare, the first edition by Purcell especially so. (2)

Cowper (William). Myotomia Reformata: Or an Anatomical Treatise on the Muscles of the Human Body... To Which is Prefix`d an Introduction Concerning Muscular Motion, 1st edition, 1724, engraved frontispiece, engraved table, 67 engraved plates, including plate XIII in two states, engraved illustrations, plate XIV with marginal repair, a few minor spots, modern black morocco-backed boards, folio. This work made a modest first appearance in 1694 as an octavo, but Cowper worked until his death on a new edition which was finally published posthumously under the supervision and at the expense of Richard Mead (1673-1754). This sumptuous folio with engravings after Rubens and Raphael and an ingenious set of historiated initials ranks among the most artistic anatomical atlases of the period` (G-M 392.1). (1)

Cramer (Johann Andreas). Elements of the Art of Assaying Metals. In Two Parts. The First containing the Theory, The Second the Practice of the said Art. The Whole Deduced from the true Properties and Nature of Fossils...Translated from the Latin, 1st English edition, 1741, six folding plates, faint library stamps to title and plates, library cloth, 8vo. Cramer was considered one of the greatest assayers of his time and was appointed director of mines and smelters for Brunswick, in the Harz Mountains. The work was originally published in Latin in 1739. Ferguson, Bibliotheca Chemica, volume I, p.180. (1)

Croce (Giovanni Andrea della). Chirurgiae universalis opus absolutum, 1st edition, Venice: R. Meiettum, 1596, title printed in red and black with large woodcut device, woodcut illustrations of operations and instruments, 4pp. contemporary manuscript index at end, manuscript note to front endpaper, one or two small repaired tears, light water stain and a few spots, library stamp, library cloth, edges lightly rubbed, 4to. Croce improved the instruments for trephination, and published classic woodcuts depicting the operation, including the first illustration of a neurological surgery operation actually taking place. The work is also important for Croce`s descriptions of cranial and cerebral diseases... Croce illustrated all of the instruments used before and during his own time` (G-M 4850.4, referring to his earlier Chirurgiae, libri septem, 1573); Adams C2993; Durling 1083. (1)

Crooke (Helkiah). Mikrokosmographia. A Description of the Body of Man. Together with the Controversies and Figures thereto Belonging. Collected and Translated out of all the Best Authors of Anatomy, Especially out of Gasper Bauhinus, and Andreas Laurentius, W. Jaggard, 1616, cancel title with woodcut illustrations, woodcut illustrations, initials and head and -tail pieces, lacking front blank?, occasional annotation and marginalia, one or two repairs and tears, some minor soiling, library stamps, modern burgundy morocco, folio. A reissue of the 1615 first edition, with the cancel title Jaggard and Barbican imprint and without the bifolium. Crooke heavily borrowed the text from Gaspard Bauhin`s Theatrum Anatomicum (1605, see lot 38 for another edition), with the illustrations from Vesalius via Bauhin. He incurred the displeasure of the College of Physicians for depicting conception and reproduction, which were considered indecent, even though they were after Vesalius, and despite the College`s efforts to have the publication suppressed, it went ahead with Crooke`s defiant depictions of a male and pregnant female figure on the title-page. One of the last anatomies based on continental sources before the emergence of the purely English anatomical school. Heirs of Hippocrates 405; STC 6062.2. (1)

Dalechamps (Jacques). Chirurgie francoise ..., avec plusieurs figures des instrumens ..., 2nd edition, Paris: Olivier de Varennes, 1610, title-page printed in red and black with printer`s woodcut device, engraved illustrations to text, faint library stamp to title, occasional old marginal dampstaining, presentation bookplate to the Birmingham Medical Institute from Alfred Baker to front free endpaper, with earlier inscription to Baker from a former pupil J. Smith, dated 1873, contemporary vellum, a little soiled, 4to (232 x 166mm) Considered the most important French surgical book of the sixteenth century after Pare`s Dix livres de chirurgie (1564), the first edition of 1573 contains a commentary on Paul of Aegina, Hippocrates, Celsus, Aetius of Amida, Avicenna and Albucasis. This second edition augments this with the edition of Girault`s and Riolan`s works. (1)

Dease (William). Observations on Wounds of the Head. With a Particular Enquiry into the Parts Principally Affected, in those who Die in Consequence of such Injuries, 1st edition, Dublin, 1776, 175pp., library stamp to title, bound with Hulme (Nathaniel), A Safe and Easy Remedy, Proposed for the Relief of the Stone and Gravel, the Scurvy, Gout, &c. And for the Destruction of Worms in the Human Body..., 3rd edition, Dublin, 1780, 79pp., a few light spots, library cloth, chip at spine head, 8vo. Dublin surgeon William Dease`s first work, his other works being on midwifery and venereal disease. (1)

Descartes (Rene). De homine figuris et latinitate donatus a Florentio Schuyl, 2nd edition, Leiden: Hack, 1664, printer`s woodcut device on title, ten engraved plates including some folding (the first with two lift-up flaps), numerous engravings and woodcuts in text, library stamp to title and plates, title and a few text leaf foremargins marked with numerous hair-line blue ink(?) streaks, some occasional light browning, a little worming to upper outer corners away from text, inner hinges broken, library cloth, 4to (198 x 152mm) Descartes was prepared to publish this book in 1633 but decided to withhold it when he learned of Galileo`s condemnation by the Church. As a result, the first edition was not published until 1662, twelve years after Descartes` death. The Latin translation preceded the French edition by two years, the present second Latin edition appearing the same year as the first French edition. It is sometimes called the first book on physiology...` (Heirs of Hippocrates 453); G-M 574 (1st edition); Krivastsy 3121; Waller 2376. (1)

Deventer (Hendrik van). Observations importantes sur le manuel des accouchemens. Premiere [-seconde] partie, ou l`on trouve tout ce qui est necessaire pour les Operations qui les conernent, & l`on fait voir de quelle maniere, dans le cas d`une necessite pressante, on peut, sans avoir recours aux Instrumens, remettre dans une situation convenable, ou tirer par les Pieds, d`une Matrice Oblique, ou Directe, les Enfans mal situes, vivans, ou morts, sans les endommager, ni la Mere, 2 parts in one, Paris: Pierre Prault, 1733, half-title, forty engraved plates on 37 leaves (complete, including one folding with short closed tear), continuous pagination throughout volume, errata leaf present at rear of volume, closed tear to lower blank margin of leaf eiii, ink library stammp to title and plates, some dampstaining to margins, occasional spotting (mostly at front and rear), upper pastedown with presentation label to BMI by Dr. Wade, modern calf gilt, 4to, together with Operationum chirurgicarum novum lumen exhibentium obstetricantibus, 2 parts in one, 2nd edition, Leiden, 1733, folding engraved portrait frontispiece, 37 engraved plates, some folding, one or two tears, occasional minor soiling, library stamp, BMI presentation label from Dr Smallwood Savage, contemporary vellum, dust-stained, 4to. Hendrik Van Deventer (1651-1724) was born at The Hague. He was one of the founders of modern obstetrics and studied midwifery and orthopaedics. He contributed greatly into the research of the pelvis and the effects of abnormalities which affected labour. This work was first published in the Dutch language in 1696. (2)

Dodoens (Rembert). A Niewe Herball, or Historie of Plantes, wherin is contayned the whole discourse and perfect description of all sortes of herbes and plantes, their diuers [and] sundry kindes, their straunge figures, fashions, and shapes..., 1st English edition, London [i.e. Antwerp: Printed by Henry Loe, sold] by my Gerard Dewes, 1578, title within decorative woodcut border, woodcut illustrations throughout, lacks leaf *6 at end of first quire with portrait to verso and final leaf (3Y4) with final page of index and colophon to verso, some early ownership names (Thomas Watkins and William Bransby) and scattered marginalia, occasional library stamps including one faint one to title (foremargin closely trimmed, some old ownership names and deletions at head and foot), some soiling and a few marginal repairs without loss of text, modern moroccco gilt, folio (285 x 183mm) Nissen 516; STC 6984. (1)

Dolaeus (Johann). Encyclopaedia, medicinae theoretico-practicae, qua tam veterum, quam recentiorum, Paracelsistarum nempe, Helmontianorum, Willisianorum, Sylvianorum, Cartesianorum, de causis & curationibus morborum sententiae exhibentur..., 1st edition, Frankfurt: F. Knoch, 1684, engraved portrait frontispiece, title printed in red and black (dust-soiled), blank before main text present, double column, some spotting, soiling and old dampstaining, a little worming to upper margins of last few leaves not affecting text, library stamp to portrait and title, early ownership signature of Edward Baldwin to portrait recto (dated 1709) and title, modern quarter calf gilt over marbled boards, 4to, together with Ettmuller (Michael), Opera omnia theoretica et practica..., 4 parts in one volume, 1st edition, Sam Smith, 1685, title printed in red and black with imprint pasted on at foot (slightly soiled and trimmed at upper margin shaving lettering of author`s name), four-page index bound at front, some browning and old dampstaining throughout, library stamp and early ownership signature of Dan: Kenrick to title, library cloth, upper cover and first three leaves detached, spine torn, 4to. 1) Rare first edition of this medical encyclopaedia by the German physician Dolaeus, translated into English by William Salmon and published as Systema Medicinale in 1686. 2) Wing E3384A. (2)

Estienne (Henri). Dictionarium medicum, vel., expositiones vocum medicinalium..., 1st edition, [Geneva]: Henricus Stephanus, 1564, printer`s woodcut device to title (old paper repair to upper margin not affecting printed text), Greek text, some soiling and dampstaining throughout, heaviest to first and last few leaves and upper inner margins, several oval library stamps to lower margins including title, sometimes touching text, library cloth, rubbed and soiled and upper joints weak, 8vo (164 x 100mm) Consists of Estienne`s Vocabulorum medicinalium expositiones Graecae, and his edition and translation into Latin of various other related works. G-M 6791; Durling 1402; Adams D524. (1)

Eustachi (Bartolomeo). Opuscula anatomica. De renum structura, officio, & administratione. De auditis organis. Examen offium. De motu capitis. De vena...& de dentibus, 2nd edition, Leiden: Apud Johannem vander Linden, 1707, [12],358;[6],98;[12],47 pp., general title printed in red & black, ten folding engraved plates, last portion of text lightly dampstained affecting final two plates, library bookplate to pastedown and early ink ownership markings dated 1808 to front free endpaper, contemporary blind-tooled vellum, some dust-soiling, 8vo. A reprint of the 1564 Venice first edition of this compilation of Eustachi`s works on the teeth, kidney, ear, and venous system. He was among the first to study the teeth in any detail, and his treatise here contains an early description of the first and second dentitions as well as the tooth`s basic composition of enamel and dentin. Heirs of Hippocrates 322 (1st edition). (1)

Eustachi (Bartolomeo). Tabulae anatomicae, edited by Giovanni Maris Lancisi, 1st edition, Rome: F. Gonzaga, 1714, title with engraved vignette after Pier Leone Ghezzi, 47 fine copper-engraved plates after Eustachi and Pier Matteo Pini, (bound without the unnumbered graduated scale plate), woodcut initials, title detached, library stamps, occasional light spotting, library cloth, small tear at head of spine, folio, (375 x 250mm) Only the first eight plates were issued during Eustachi`s lifetime (for his Opuscula Anatomica, 1564), the whole series of 47 plates prepared in 1552 for Eustachi`s intended work De Dissensionibus ac Controversiis Anatomicis. The other thirty-nine plates (with framed rules on three sides to provide coordinates for reference), remained unprinted and forgotten in the Vatican Library until discovered in the early 18th century, and were then presented by Pope Clement XI to his physician, Giovanni Maria Lancisi... These copperplates are more accurate than the work of Vesalius. Singer was of the opinion that had they appeared in 1552 Eustachius would have ranked with Vesalius as one of the founders of modern anatomy. He discovered the Eustachian tube, the thoracic duct, the adrenals and the abducens nerve, and gave the first accurate description of the uterus. He also described the cochlea, the muscles of the throat and the origin of the optic nerves` (G-M 391); Norman 740; Wellcome II, p. 536. (1)

Eustachi (Bartolomeo). Tabulae anatomicae clarissimi viri Bartholomaei Eustachii quas e tenebris tandem vindicatas et Clementis Papae XI, Munificentia dono acceptas, praefatione, ac notis illustravit Joh. Maria Lancisius, second Rome edition, Rome: L. & T. Pagliarini, 1728, engraved ornamental frontispiece with vignette portrait of Eustachius, small tear with loss to upper outer corner outside of plate impression, old adhesion marks from previous bookplate removal to frontispiece verso, title-page printed in red and black with engraved vignette of a dissection scene, old ownership signature of Robt. Smith to upper margin, forty-seven fine engraved plates with numbered rule borders (for use as coordinates in conjunction with text), faint library stamp to title and all plates, erasure mark to blank area within plate impression of plate 18, some spotting, Johnstonre armorial bookplate to front pastedown, contemporary vellum, soiled and some wear, folio (372 x 250mm) G-M 391; Norman 740 (both citing first edition, 1714). (1)

Fabrizzi (Girolamo). [Opera physica anatomica: de formato foetu, venarum ostiolis, formatione ovi, & pulli, locutione, & eius instrumentis, brutorum loquela...], 5 parts in one volume, 1st collected edition, Padua: Roberti Meglietti, 1625, separate title to each part but lacks general title and title to Formatione ovi`, first title De Formato foetu` dated 1600 and printed within engraved decorative border (early inscription to upper margin trimmed away), forty-nine engraved plates including twelve double-page (these all on new guards), some larger plates closely trimmed at margins, some offsetting to text, colophon for first work dated 1604 with errata leaf bound after, title-pages to third, fourth and fifth works with printer`s device and imprint of Lorenzo Pasquati, each dated 1603, index leaves to Locutione` and Brutorm loquela` misbound, lacks final blank, faint library stamp to first title and all plates, some occasional spotting and soiling and a few minor marginal tears and archival repairs, ownership signature of Rich[ar]d Henry Morris, dated 1778, to preserved old front free endpaper, Birmingham Library bookplate to front pastedown, modern calf, rubbed, folio (394 x 260mm) Fabrizzi, (Hieronymus Fabricius ab Aquapendente), was professor of medicine at Padua, and the influential teacher of William Harvey. The works here use the sheets of the original editions, with no conclusive indication that these were issued as the Opera of 1625, and are bound up as follows: De formato foetu (G-M 465; Norman 751, 1600 edition); Formatione ovi, & pulli (Norman 752, 1621 edition); Venarum ostiolis (G-M 757; Norman 750, 1603 edition); De locutione & eius instrumentis (Norman 749, 1603 edition); Brutorum loquela. Wellcome I, 2126. Collation: pi2 [-pi1 general title], a-b2, A-E4, F-I2, K4 [K4 a cancel with corrected plate], L-O2, P4, Q2, R-Z4, Aa2; A-H4, I2 [+1, errata], 4 leaves plates [-pi1, title]; pi1, A4, B-C2, D4; pi1, **2, D3/4, A-C4, D1/2; pi2, D3, A-C4 [-D4 blank]. (1)

Fabrizzi (Girolamo). Opera omnia anatomica & physiologica, Leipzig, 1687, half-title, title printed in red and black with woodcut device, 62 copper-engraved plates (some folding), illustrations, library stamps, one or two closed tears, some spotting and browning, BMI presentation label from the Executors of the late R. Middlemore to front endpaper, contemporary vellum, upper joint repaired, dust-soiling, folio. First collected works edition of influential Paduan anatomist and surgeon Hieronymus Fabicius ab Aquapendente (1537-1619), friend of Galileo and teacher of William Harvey, Julius Casserius and Adriaan van den Spiegel. (1)

Falloppio (Gabriele). Opera omnia..., 2 volumes in one, Frankfurt: Heirs of Andreas Wechel, 1600, printer`s woodcut device to both titles, index to each volume, library stamps to title and a few lower margins, some spotting and old dampstaining (mostly to upper inner margins) throughout, ownership signature of Albert Kyper to title lower margin, cut signature of James Johnstone pasted to front pastedown (endpapers renewed), contemporary blind-stamped vellum over boards, rebacked with original spine relaid, rubbed and soiled, lower outer corner repaired, folio (365 x 218mm) First published in 1584, the appendix to this edition was published as volume 3 in 1606. Provenance: Albert Kyper, professor of medicine at Leiden, published several medical works between 1615 and 1660, including Institutiones medicae and Anthropologia, corporis humani. Adams F135. (1)

Fioranvanti (Leonardo). Three Exact Pieces..., viz. His Rationall Secrets, and Chirurgery, Reviewed and Revived. Together with a Book of Excellent Experiments and Secrets, Collected out of the Practises of Severall Expert Men in Both Faculties, Whereunto is Annexed Paracelsus his One hundred and fourteen experiments, with certain excellent works of B.G. a Portu Aquitano, also Isaac Hollandus his Secrets concerning his vegetall and animall work, With Quercetanus his Spagyrick antidotary for gun-shot, 4 parts in one volume, 1st edition, 1652, fleuron border to main title (minor nicks to foremargin), three part-titles, leaves (bb)1&2 (To the Reader and Contents to second book) bound at end of preliminary leaves to first book, paper flaw to lower margin of 2K1 with resultant closed tear touching catchword to recto and the` in final line verso, faint library stamp to title, some light browning, old dampstains and fraying to foremargin extremities, partly loose and broken in library cloth, 4to (183 x 138mm) A better than usual copy of this first edition of a compilation of texts, primarily translations of the popular Fioravanti, and more importantly Paracelsus, by John Hester, first published nearly a century earlier. Norman 797; Sudhoff, Bibliographia Paracelsica 370; Wing F953. (1)

Floyer (John). The Physician`s Pulse-Watch; or, an essay to explain the old art of feeling the pulse, and to improve it by the help of a pulse-watch. In three parts... To which is added an extract out of Andrew Cleyer, concerning the Chinese art of feeling the pulse, volume 1 (of 2, as often), 1st edition, 1707, single advert leaf after contents, light library stamp to title, some spotting, late 19th-c. cloth, slightly rubbed and soiled, 8vo. G-M 2670. Floyer, a Lichfield physician, was the first to count the pulse with the aid of a watch and to make regular observations on the pulse rate. A second volume was published in 1710 and contained the first English translation of Cleyer`s book on Chinese pulse-lore. (1)

Floyer (John). A Comment on Forty Two Histories Discribed by Hippocrates in the First and Third Books of his Epidemics, 1st edition, 1726, title ruled in red (faint library stamp), some spotting and browning, errata deleted and corrected in text in an early hand, three leaves ms. index at front (initialled R.M.) and two leaves notes in the same neat hand at rear, modern half morocco gilt over marbled boards, 8vo, together with A Treatise on Asthma, Divided into Four Parts, 3rd corrected ed., 1726, some spotting and numerous library stamps, library cloth, rubbed, plus Pharmako-Basanos, or the Touch-Stone of Medicines, volume 1 only (of 2), [1687], three advert and errata leaves at rear, library stamps, some heavy dampstaining and soiling at front and rear, modern morocco gilt with Johnstone library bookplate preserved, 8vo (3)

Foes (Anuce). Oeconomia Hippocratis, alphabeti serie distincta..., 1st edition, Frankfurt: Heirs of Andreas Wechel, 1588, printer`s woodcut device to title and final leaf verso, engraved medallion portrait of the author to title verso, woodcut initials and head-pieces, Greek and Latin text, double column, early inscriptions to title and some scattered underscoring, some spotting and old dampstaining throughout, library stamps to title and to lower margins of several rectos, ownership inscription and mongoram stamp of James Johnstone to front pastedown, contemporary vellum, soiled and upper joint split, folio (336 x 205mm) This large concordance of Hippocrates` works, listing important words in Greek with text references and commentary, took Foes over forty years to complete. It was the standard reference used for studying Hippocrates` writings and for etymological studies until the appearance of Littre`s definitive work some 250 years later. The fine medallion portrait of Foes on the verso of the title-page was executed by the French engraver Pierre Woeiriot (ca. 1531-ca. 1589) and appears only in first editions of the book` (Heirs of Hippocrates 348); Adams F660; Durling 1589; G-M 6793; Waller 3101; Wellcome 2334. (1)

Fontana (Felice). Treatise on the Venom of the Viper; on the American Poisons; and on the Cherry Laurel, and some other Vegetable Poisons..., Translated from the Original French... by Joseph Skinner, 2 volumes, 1st English edition, 1787, half-titles, ten folding engraved plates, title with library stamp and stamps to plates, some dampstaining and spotting mostly to volume one, text block to volume one split, library cloth, 8vo, together with Mead (Richard), A Mechanical Account of Poisons, in Several Essays, 3rd edition, 1745, four engraved plates (including one folding), engraved illustration to title and final leaf, library stamp to title and plates, some light dampstaining, contemporary calf, upper board detached, lower joint cracked and some wear, 8vo, plus a fourth edition of the same work published 1747, in library cloth. G-M 2103 for the first title, which was originally published in Italian in 1767. The starting point of modern investigations of serpent venoms`. (4)

Fracastoro (Girolamo). De sympathia et antipathia rerum liber unus, De contagione et contagiosis morbis et eorum curatione, libri tres, 2nd edition, Lyon: Gulielmum Gazeium, 1550, printer`s woodcut device to title, woodcut initials, colophon leaf at rear, some old marginalia and underscoring, faint library stamp to title (slightly soiled), dampstaining to final leaves, old illuminated leaf on paper and later old endpaper at rear, the latter with closed tear and ownership inscription of Edward Stanhope (probably the main annotator of the text), BMI presentation bookplate from Dr [Willoughby] Wade to front pastedown, contemporary blind-panelled calf with the cypher W to both covers, rebacked with original spine relaid, 16mo. The second edition of Fracastoro`s classic work on the germ theory of infectious disease. Although his medical poem on syphilis is perhaps more widely known, the present work is a far more important contribution to science, establishes Fracastoro as one of the foremost scientists of all time, and earns him the title of founder of modern epidemiology. De contagione contains the first scientifically reasoned statement of the true nature of infection, contagion, and the germ theory of disease and is the foundation of all modern views on the nature of infectious diseases. The influence of Fracastoro`s ideas was evident during the seventeenth and eighteenth centuries in the work of Francesco Redi, Giovanni Maria Lancisi, and Antonio Vallisnieri as they contributed to a greater understanding of the nature of infection. Fracastoro`s influence is also clearly reflected in the work of such modern scientists as Louis Pasteur, Joseph Lister, and Robert Koch as they broadened and furthered man`s knowledge of infectious diseases` (Heirs of Hippocrates 174); Durling 1636; G-M 2528; Norman 827; Osler 2652; Waller 3163; Wellcome 2393 - all citing 1546 first edition. (1)

Fracastoro (Girolamo). Opera omnia, 2nd collected edition, Venice: Giunta, 1574 [colophon dated 1583], woodcut printer`s device to title and colophon leaf at rear, woodcut portrait and diagrams to text, some marginal old dampstaining and slight soiling to first and last leaves, faint library stamp to title and portrait leaf recto and verso, BMI presentation bookplate from Dr [Willoughby] Wade, library cloth, slightly rubbed on joints, 4to (227 x 169mm) First published in 1555 this works edition includes his principal astronomical, philosophical, poetic and medical treatises. Adams F818; Durling 1632; Wellcome I, 2397. (1)

Freind (John). Opera Omnia, 1st edition, 1733, licence leaf, half-title, engraved portrait frontispiece, title with engraved vignette, engraved headpiece and initial, a few light spots, library stamp, contemporary mottled calf, rebacked, a little rubbed, folio. Freind was the first English historian of medicine` (Garrison-Morton). Whilst imprisoned in the Tower of London for high treason (he was innocent), Prime Minister Sir Robert Walpole was suffering from renal calculi and called in Freind`s great friend Richard Mead, who refused Walpole treatment until Freind was released, which happened rather speedily. (1)

Fuller (Francis). Medicina Gymnastica: Or, A Treatise Concerning the Power of Exercise, with Respect to the Animal Oeconomy, and the Great Necessity of it in the Cure of Several Distempers, 1st edition, Robert Knaplock, 1705, imprimatur leaf before title, library stamp and ownership signature of John Freer to title, some spotting, marginal dampstaining and soiling, especially to first and last leaves, library cloth, rubbed and slightly frayed at head of spine, 8vo. The first treatise in English on the use of therapeutic exercise. The first edition is far less common than the second enlarged edition of the same year. ESTC T140184. (1)

Geminus (Thomas, c. 1510-1562). Compendiosa totius anatomie delineatio aere exarata, 1st or 2nd English issue, Imprynted at London by Nycholas Hyll dwellynge in Saynte Johns streate, for Thomas Geminus, [1553], forty engraved plates, Adam & Eve double-page plate with figures trimmed close and just touching a fingertip of each, relaid on to two facing leaves, lacks the armorial, architecutral and allegorical engraved title here supplied in an early and possibly near-contemporary manuscript facsimile using silverpoint and sepia ink, manuscript details of the 1559 imprint incorporated at foot, central panel excised and left blank (Royal Coat of Arms in the 1553 editions, portrait of Queen Elizabeth I in the 1559 edition), a few minor tears and small loss to lower right margin, the whole leaf relaid, dedication leaf for King Edward VI, slightly browned and soiled, old inscription of Watt Tooke(?) dated 167[?] to upper outer corner and slightly trimmed, dedication leaf verso To the ientill readers and Surgeons of Englande`, dated 1552, tiny holes to leaves A1 (old ink spash), G1 and G6, split to lower margin of B7, old ink marginalia to C1 verso, archival closed tear repairs to F1 including horizontal split across image and lower outer corner of text block, marginal paper repair to same leaf not affecting text, first cerebral engraved plate trimmed into plate impression touching image, I2 duplicated, upper marginal wormholes not affecting text or plates of leaves I3 to end, final leaf slightly browned and chipped at inner margin, with two small tears and loss not affecting text, leaf reattached at inner margin to endpaper, some other general spotting and soiling, old marginal dampstaining confined largely to preliminaries, signatures A-B and final leaf, library cloth, folio (369 x 258 mm) The Latin Geminus of 1545 and the English edition of 1553 were the first illustrated textbooks of anatomy to be published in this country and the forty illustrations were printed from the first copper plates to be executed here. Encouraged by the success of his Latin edition of Vesalius, Geminus was persuaded, possibly by Vesalius`s old roommate John Caius, to prepare a version of the Vesalian plates with English text for the benefit of `unlatined surgeons.` As he doubted his proficiency in English, Geminus sought the aid of Nicholas Udall, dramatist (he wrote the comedy Ralph Royster Doyster) and prebendary of Windsor, to translate the characterum indices of the Vesalian plates. The English text chosen to accompany the plates was an early translation of the Surgery of Henri de Mondeville, which Thomas Vicary, surgeon to Henry VIII, had used almost word for word in his own Anatomie of the bodie of man (1548). The text was rearranged in Geminus`s book to follow the traditional order of conducting a dissection, beginning with the viscera and ending with the bones in order to dissect first those parts which would most quickly putrefy` (Norman 887). Collation *2[-*1], A6, B7, C-I6 [I2 duplicated], K2; forty engraved plates. Additionally, bound before and after the dedication leaf are to be found three pages of Explanation leaves relating to the fugitive sheet of a seated Adam and Eve with flaps (see Russell 308). Two copies of the first sheet have been used to show recto and verso; the verso of sheet two was blank. Each page is slightly cut down at head and foot, trimmed close at the foremargin affecting text in most lines and relaid on three sheets. The text of this impressive work is in double column, black letter, and with crible metal-cut initials. A watermark of a pot or gauntlet and star is visible in many of the sheets. The illustrations comprise the external anatomy of Adam and Eve (here separated and mounted on two sheets), three skeletal engravings, sixteen muscular engravings, five arterial and venal engravings, four neural engravings, six engravings of organs, four cerebral engravings and one engraving of ocular parts and surgical instruments. These are all based on Vesalian woodcuts to be found in the Fabrica and the Epitome. The first edition in English is extremely rare, the copies produced being so well-used that few have survived in any semblance of good condition. The Norman copy of the undated first issue claimed to be the only complete copy in private hands. There are two English versions of 1553, (STC 11715.5 & 11716), that with an undated title-page being claimed as the first issue. Both are otherwise identical and bear the same imprint at the rear as found in this copy, and not found in any other edition identified. The matter is further complicated by the presence of the three added pages of explanation to accompany the fugitive plate of a seated Adam and Eve (not included in this copy), that though not part of the collation, are often found in copies of the 1559 edition. This copy in the main body of text (excepting the last leaf which is slightly browned and spotted and separated from the main body of text) is in very good order with only the presence of the usual light Birmingham Medical Institute library stamps affecting the freshness of the plates. For further discussions of this remarkable volume see Russell 830-833 (and 308), Cushing VI.C.-2, Norman 887. See also an article by S.V. Larkey, The Library, XIII (1932-33), pp. 367-94. (1)

Gibson (Thomas). The Anatomy of Humane Bodies Epitomized, 6th edition, 1703, imprimatur before title, twenty engraved plates, some spotting or browning throughout, library stamps to title and plates, old ownership signatures of Thomae Gilberd dated 1738 and Danielis Leblon, also presentation bookplate to the BMI from Dr Blackall, contemporary panelled calf, neatly rebacked and recornered, together with a fifth edition of the same work, 1697, twenty engraved plates, lacks imprimatur and first leaf of To the Reader (A3), old dampstaining throughout, library stamps to title and plates, library cloth, a little frayed at head of joints, both 8vo. Russell 319 & 318. (2)

Giffard (William). Cases in Midwifry, Revis`d and Publish`d by Edward Hody, 1st edition, 1734, three folding engraved plates (first plate signed A. Motte), occasional light water stains, library stamps, BMI presentation label from Oliver Pemberton, modern red half morocco, spine a little faded, 4to (234 x 180mm) Contains, under Case 14, the earliest published record of the use of the hitherto secret Chamberlen forceps, in 1726, together with illustrations of two variant types. Giffard is considered the first English obstetrician to publish substantial contributions to clinical midwifery.` (G-M 6156.3). He was the first to use the Mauriceau-Smellie-Veitm method of extracting the aftercoming head and performed the now termed Ritgen Manoeuvre (for the prevention of tears to the perineum during delivery. Norman 902; Wellcome III, p.114. (1)

Glisson (Francis). Anatomia hepatis, cui praemittuntur quaedam ad rem anatomicam universe spectantia. Et ad calcem operis subjiciuntur nonnulla de lymphae-ductibus nuper repertis, Amsterdam: Johann Ravestein, 1659, printer`s vignette woodcut device to title (faint library stamp), two folding en. plates, lacks additional engraved title, library cloth, a few nicks to spine ends, 12mo (125 x 75mm) First published in 1654 (G-M 972) this is the second Latin edition of this classic work on the liver. Osler 2759; Waller 3583; Cushing G289. (1)

Graaf (Regnier de). De succo pancreatico: Or, A Physical and Anatomical Treatise of the Nature and Office of the Pancreatick Juice..., translated by Christopher Pack, 1st English edition, 1676, woodcut printer`s device to title (some spotting and browning to gutter margin, two faint library stamps, upper outer corner torn away affecting rule border, three folding engraved plates, library stamps and first with closed tear repair not affecting plate, heavy spotting throughout, library cloth, a little rubbed and soiled, 8vo (164 x 102mm) Krivatsy 4913; Norman 924; Wing G-1463. (1)

Graunt (John). Natural and Political Observations Mentioned in a Following Index, and Made Upon the Bills of Mortality, with Reference to the Government, Religion, Trade, Growth, Air, Diseases, and the Several Changes of the Said City, the Third Edition, Much Enlarged, John Martyn & James Allestry, 1665, two folding tables, both with closed tear repairs to verso, the larger table with further fold wear and minor damage to lettering, some old dampstaining throughout, marginal chipping and browning to first and last few leaves, outer margin of E8 repaired with some loss of text affecting nine lines, small tear to lower outer corner of H4 touching one letter of final line verso, lacks imprimatur leaf before title and both blanks (a8 and O8), modern quarter morocco gilt over marbled boards, 8vo (161 x 99mm) First published in 1666, Graunt`s observations on the bills of mortality led to the publication of the first life table to be based on real mortality data. Designed to provide a warning against the plague epidemic, the bills of mortality did not give the age of death, but did provide the cause of death, and from this Graunt was able to estimate that 36% of all deaths concerned children under the age of six. Among the wide range of deaths listed in the Table of Casualty are the more common as well as Excessive drinking, Fainted in a Bath, Grief, Killed by several Accidents, Lethargy, Leprosie, Overlaid and starved at Nurse, and Suddenly. Goldsmiths` 1757; Kress 1155; Wing G1600. (1)

Grew (Nehemiah). The Anatomy of Plants. With an Idea of a Philosophical History of Plants, and Several Other Lectures, Read Before the Royal Society, 1st edition, printed for the author by W. Rawlins, 1682, licence leaf before main title, 83 copper-engraved plates, including four double-page, pp. 213-220 mispaginated, erratic signatures, occasional light water stains and spotting, library label, modern calf, a little rubbed, folio. First collected edition of Grew`s earlier works (The Anatomy of Vegetables; An Idea of a Phytological History and The Comparative Anatomy of Trunks), the book is the first textbook on plant anatomy with fine and accurate plates, as observed by Grew using a microscope, and containing the first microscopic description of pollen. Along with Malpighi, Grew is considered the founder of plant anatomy and demonstrates that the normal internal structure of plants are made of `cells`, first observed by Robert Hooke in 1665. Henrey 162; Nissen 758; Norman 946. (1)

Guillemeau (Jacques). The Frenche Chirurgerye, or All the manualle operations of Chirurgerye, with divers, & sundrye figures, and amongst the rest certayne neufownde instrumentes, verye necessarye to all the operationes of Chirurgerye ..., now truelye translated out of Dutch into Englishe by A. M., Dordrecht, Isaac Canin, 1597 [colophon dated 1598], engraved title with large full-page engraved royal coat-of-arms to verso, some soiling and marks, with several 17th century ownership signatures in ink, and close-trimmed to fore-margin with several repaired tears, thirteen full-page engraved plates of human anatomy and various medical instruments, some soiling, 17th century ink annotations to margins, folio 28 (G4), with closed tear to upper portion repaired, lacks final leaf of index, with colophon to verso, later 19th century maroon cloth by C. Cooper of Birmingham, with their ticket to front pastedown, rubbed and a little frayed to extreme head and foot of spine, with Birmingham Medical Institute gilt stamp at foot, folio (36 x 23.5cm) STC 12498. G-M 3669 for the first edition in French of 1594. A pupil of Ambroise Pare, Jacques Guillemeau (1550-1613), was an oculist, obstetrician, and surgeon to Charles IX and Henry IV of France. He wrote the first French book on ophthalmology in 1585, entitled TraitŽs des Maladies de l`Oeil, and his treatise on child birth, entitled L`Heureux Accouchement des Femmes, first published in 1609, was quickly translated into English as Child-birth, or The Happy Deliverie of Women in 1612. (1)

Haller (Albrecht von). A Disseration on the Sensible and Irritable Parts of Animals, 1755, half-title and final leaf verso (advertisements) dust-soiled, bound with Pathological Observations, Chiefly from Dissections of Morbid Bodies, 1756, three folding plates, advert leaf at rear, lacks half-title, bound with La Condamine (Charles Marie de), A Discourse on Inoculation, read before the Royal Academy of Sciences at Paris, the 24th April 1754, [translated by Matthew Maty], 1st English edition, P. Vaillant, 1755, engraved vignette to title, closed marginal tears to final leaf into text without loss (archivally repaired), lacks half-title, library stamps to titles of first two works, plate versos and occasionally to lower margins elsewhere, library cloth, 8vo. La Condamine (1701-1774) was extremely active in the promotion of the inoculation of smallpox. This work was originally published in French a year earlier and is one of the earliest Western works on the subject. (1)

Harvey (William). Exercitationes de generatione animalium. Quibus accedunt quaedam, De partu: De membranis ac humoribus uteri: et De conceptione, 1st edition, Du Gard for O. Pulleyn, 1651, engraved frontispiece facing (to recto and facing pi1 as sometimes, see Keynes) of Jove seated on a pedestal and holding in his hands an egg inscribed ex ova omnia`, a little trimmed at lower foremargin with loss of rule border, engraved head-pieces and initials throughout, first and last blank and that at C4 all present, ownership signature of Joesph Bromehead on title with his manuscript note to frontispiece verso Editio princeps`, ownership signature of J[ohn] Braxton Hicks dated 1866 to front pastedown and with small presentation bookplate from Hicks to the BMI pasted to initial blank recto, contemporary sheep gilt, rebacked with original spine relaid, some edge wear, 4to (214 x 160mm) After the publication of De motu cordis, Harvey turned his attention to the study of generation. Even if Harvey had not discovered the circulation of the blood, his remarkable work on embryology would have placed him in the front ranks of biological scientists. Without benefit of the compound microscope, his work was necessarily limited; nevertheless, nothing comparable had been done since Aristotle. He disbelieved the previously-held doctrine of `preformation` of the foetus, maintaining instead that it proceeds from the ovum by gradual building up of its parts. Always slow to publicize his findings, Harvey was only after some years persuaded by his friend, Sir George Ent, to put them into print. The first edition was published in London in 1651, followed by three Amsterdam editions of the same year` (Heirs of Hippocrates 436: 1st Amsterdam edition, 1651). G-M 467; Keynes, Harvey, 34; Norman 1011; PMM 127. Wing 1091. Provenance: Joseph Bromehead (1748-1826), was educated at Queen`s College, Oxford (BA 1768, MA 1771), and served as Curate of Eckington, Derbyshire, until his death. He wrote hymns and also published The Melancholy Student, An Elegiac Poem` (1769) and An Oration on the Utility of Public Infirmaries: Occasioned by the opening of the Radcliffe Infirmary at Oxford` (1772). John Braxton Hicks FRCP, FRS (1823-1897). (1)

Harvey (William). Exercitationes de generatione animalium..., Amsterdam: Louis Elzevir, 1651, lacks additional engraved title and final blank, library stamp to title with printer`s device, occasional pen or pencil marginalia and underscoring, library cloth, 12mo (125 x 74mm) The first edition was published in London in 1651, followed by three Amsterdam editions of the same year. This Elzevir edition is believed to be the first of the three Amsterdam editions` (Heirs of Hippocrates 416); G-M 467 (London edition, 1651); Keynes 35 or 36 (from imprint on engraved title); Osler 712; Russell 376; Waller 4119; Wellcome III, p. 220. (1)

Harvey (William). Opera sive exercitatio anatomica de motu cordis et sanguinis in animalibus, atque exercitationes duae antomicae, de circulatione sanguinis ad Joannem Riolanum filium, tumque exercitationes de generatione animalium, quibus praefationem addidit Bernardus Siegfried Albinus..., 2 parts in one volume, editio novissima, Leiden: Johannes van Kerckhem, 1737, general half-title and half-title to second part, titles printed in red and black with engraved vignette, double-page engraved plate with four figures in part one, Y1 (Libri aliquot medici et juridis quos excudit...) misbound after **3 at end of unnumbered preliminary leaves in part one, lacks blanks at end of both parts (Y2 and 3K2), library stamps throughout to lower margins and including general half-title, first full title and plate versos, some spotting, library cloth, 4to (189 x 152mm) First collected edition in Latin. Harvey`s chief works in Latin have only twice been printed in a collected form, first by van Kerckhem at Leiden in 1737, and secondly by Bowyer for the Royal College of Physicians in 1766` (Keynes, p. 100). The anatomist Albinus edited several works editions including the collected works of Vesalius (1725), see lot 418 below. This Albinus Harvey is rare though not as rare as the separately issued 1736 edition of volume 1: This form of van Kerckhem`s edition is rare, the sheets of the greater part of the issue having been published in 1737 as Part I of the Opera` (Keynes 14n). Keynes 46. (1)

Havers (Clopton). Osteologia Nova, or Some New Observations of the Bones, and the Parts belonging to them, with the Manner of their Accretion and Nutrition, 1st edition, 1691, imprimatur leaf before title, two engraved plates including one part-folding, publisher`s ad. leaf at rear, faint library stamps to title and plates, old inscription struck through on title, modern morocco gilt over marbled boards, spine slightly faded, 8vo (179 x 110mm) The first complete and systematic study of the structure of the bones. Havers gave the first full description of the microscopic structure of the bone canals made for the passage of blood-vessels, named `Haversian canals` in his honor` (Norman 1024); G-M 387; Krivatsy 5363; Wing H1162. (1)

Helmont (Jean Baptiste van). Opuscula medica inaudita, I. De Lithiasi. II. De Febribus. III. De Humoribus Galeni. IV. De Peste, 3 parts in one volume, 1st edition, Cologne: Jodocum Kalcoven [Amsterdam: Louis Elzevir], 1644, general title-page and three part titles (Part Two title stating second edition`), errata leaf at rear of each part and separate approbation leaf at end, cancelled approbation leaf (but no blank) present at end of part two, faint library stamp to main title-page (dust-soiled), dampstaining to upper and outer margins of first part, heavy browning to lower half of most leaves of final part, old manuscript contents list to front endpaper, library cloth, 8vo. Krivatsy 5441; Norman 1048 (2nd edition, 1648, bound as second part of the first collected edition of Ortus medicinae). (1)

Heurne (Johan van). Praxis medicinae nova ratio: qua, libris tribus methodi ad praxin medicam, aditus facillimus aperitur ad omnes morbos curandos, 1st edition, Leiden: Plantin, 1587, printer`s woodcut device to title, two (of three) folding tables, one on a modern guard and both bound before A1, woodcut illustrations in the text, old ink marginalia and inscription Bib: Harv:` to title, library stamps to title and plates, somewhat soiled at front and rear, occasional old dampstaining, archival repairs with loss of text to upper outer corners of last four leaves of index, modern morocco gilt, 4to. Rare first edition of this general treatment of the medical profession. (1)

Hewson (William). Experimental Inquiries: Part the First. Being a Second Edition of an Inquiry into the Properties of the Blood, 2nd edition, 1772, bound with Experimental Enquiries: Part the Second. Containing a Description of the Lymphatic System, 1st edition, 1774, half-titles, six engraved plates (five folding), occasional library stamps throughout, some contemporary marginal notes, library cloth, 8vo, together with Experiment Inquiries: Part the Third. Containing a Description of the Red Particles of the Blood, 1st edition, 1777, half-title, four folding engraved plates, library stamps to title and plates, library cloth, 8vo, and other related works with library markings including Robinson (Bryan), A Treatise on the Animal Oeconomy, Dublin, 1732, folding engraved plate, library cloth, 8vo, plus Pemberton (Henry), A Course of Physiology, 1773, contemporary calf, upper cover detached, 8vo, plus Simson (Thomas), An Inquiry how far the Vital and Animal Actions of the More Perfect Animals can be Accounted for Independent of the Brain, Edinburgh, 1752, two folding engraved plates, paper repair to upper edge of title, library cloth, 8vo, plus Paxton (P.), Specimen physico-medicum, de corpore humano, & ejus morbis. Or, an Essay Concerning the Knowledge and Cure of most Diseases, 1711, library cloth, 8vo, plus Wilkinson (C.H.), Essays, Physiological and Philosophical, 1798, library cloth, 8vo (7)

Hillary (William). Observations on the Changes of the Air and the Concomitant Epidemical Diseases, in the Island of Barbadoes, To Which is Added A Treatise on the Putrid Bilious Fever, Commonly Called the Yellow Fever, and Such Other Diseases as are Indigenous or Endemial, in the West India Islands, or in the Torrid Zone, 2nd edition, 1766, some spotting, heavier at front and rear, old dampstaining to gutter margins towards rear, light library stamp to title, presentation bookplate to the BMI from Dr. Blackall to front pastedown, modern quarter calf gilt, 8vo. G-M 1770 (1st edition, 1759): Hillary included good accounts of lead colic and infective hepatitis, and probably the first description of sprue`. (1)

Hippocrates. Octoginta volumina... nunc tandem per M. Fabium Caluum Latinitate donata... nunc primum in lucem aedita..., 1st edition, Rome: Franciscus Minutius Calvus, 1525, 410 leaves, title within ornamental woodcut border (untrimmed, faint library stamp at upper margin), two large woodcut initials, Roman, italic and gothic type, initial spaces with printed guide letters, old marginal pen mark to 2L5v and marginal note to 3M3r, archival closed tear repairs to upper margins of leaves H3-5 not touching text, small tear with loss to lower outer corner of leaf P2 not affecting text, a little spotting and light browning and old dampstaining to upper margins throughout, occasional library stamps to lower margins of text leaf rectos (nine in total), very minor worming to lower margins towards rear and a few trivial single wormholes to upper margins of last few leaves including colophon and final blank, armorial bookplate of Johnstone [probably John Johnstone, 1768-1836, physician and biographer] to front pastedown, 19th-c. morocco gilt, spine darkened, joints tender, slightly rubbed and soiled, folio (280 x 205mm) Although various fragments of Hippocrates` works had been published earlier in Greek and Arabic versions, these eighty works, translated for the first time from the Greek texts into Latin by Marco Fabio Calvo (d. 1527), form the first so-called `complete` Hippocrates. The editio princeps of the Greek texts was published in 1526 [at the Aldine Press]. These eighty texts, the most familiar of which is the Aphorisms, were probably written by a number of authors, but all are in the Hippocratic tradition. This historically important book, along with the massive French translation of Littre in the nineteenth century, must be regarded as the definitive Hippocrates` (Heirs of Hippocrates 10); Adams H567; Durling 2320; Norman 1076; Osler 149; PMM 55; Waller 4495; Wellcome 3177. (1)

Hippocrates. Hippocratis coi Opera quae extant Graece et Latine, veterum codicum collatione restituta, nono ordine in quattuor classes digesta, interpretationis latinae emmendatione, & scholiis illustrata, a Hieron. Mercuriali Foroliviensi, 2 volumes bound in one, Venice, Industria ac sumptibus Iuntarum, 1588, engraved general title with text printed in red and black, printed title to volume 2 in red and black present (lacking printed title to first volume), divisional half-titles, Greek and Latin text in double-column, woodcut initials, head- and tail-pieces, engraved title with careful excisions beside printed title and at foot (probably to remove ownership inscriptions), and repaired with blank paper, light water stain to top margins, and lower outer corners at front of volume, to upper outer corner twoards middle of volume and to fore-margin at rear, final three leaves with minor paper loss to lower outer corner, not affecting text, modern half calf, with small Birmingham Medical Institute name stamp to foot of spine, thick folio. Adams H565. Graesse 3, 281. Brunet 3, 170 edition assez estimee`. Durling 2318. Ebert 9728. Waller 4484. Wellcome 3175. (1)

Hodges (Nathaniel). Loimologia: or, an Historical Account of the Plague in London in 1665: with precautionary Directions against the like Contagion..., To which is added, an essay on the different Causes of Pestilential Diseases, and how they become Contagious: with Remarks on the Infection now in France, and the most probable Means to prevent its Spreading here, 2nd edition, 1720, pp.[ii]+iii-vi, 288, folding table at rear, first gathering comprising three leaves (possibly lacking front blank/half-title?), library stamp to title and two stamps to folding table, library cloth, 8vo, (G-M 5121), together with Mead (Richard), A Discourse on the Plague, 9th edition, 1744, title with ownership ink stamp of R. Nesbitt MD to lower blank margin and also faint library stamp, front blank inscribed From the Author`, occasional light spotting, library cloth, 8vo, with Harvey (Gideon), The City Remembrancer: being Historical Narratives of the Great Plague at London, 1665..., volume 1 only (of two), lacks half-title, library stamp to title, library cloth, dampstained at foot of upper board, 8vo. Nathaniel Hodges provided the best record of the Great Plague of 1665. Hodges was a physician to the City of London and medical hero of the great epidemic. The first edition was published in 1672 in Latin and translation into English 1720. (3)

Hoffmann (Friedrich). Opera omnia physico-medica ..., 6 volumes in three, Geneva: Fratres de Tournes, 1748, engraved portrait frontispiece, first title printed in red and black, library stamp to titles, some spotting, occasional browning and old dampstaining, together with Operum omnium physico-medicorum supplementum, three parts in 2 volumes, 1st edition, Geneva, 1753, plus Supplementum, 2nd revised edition, two parts in 1 volume, Geneva, 1754, half-title to part one of both editions, first title of both editions printed in red and black, library stamp to titles, some spotting, browning, and old dampstaining (somewhat heavy to lower margins of 2nd edition supplement, all contemporary mottled sheep, matching antique-style rebacks, except for 1st edition volume 1 supplement (some wear to spine and covers detached), all folio (357 x 217mm) (6)

Hunter (John). The Natural History of the Human Teeth: Explaining their Structure, Use, Formation, Growth and Diseases, 1st edition, 1771, half-title, 16 copper-engraved plates, bound with A Practical Treatise on the Diseases of the Teeth; Intended as a Supplement to the Natural History of Those Parts, 1st edition, 1778, half-title, light toning and scattered spots, library cloth, 4to. The first scientific study of the teeth and is basic to all modern dentistry` (Heirs of Hippocrates 968). This is a detailed study of the mouth, jaws and teeth with exceptionally accurate plates. Hunter correctly understood the growth and development of the jaws and their relation to the muscles of mastication. He coined the terms cuspids, bicuspids, molars and incisors` (G-M 3675-6); Norman 1116. (With Supplement 1778). (1)

Hunter (John). The Natural History of the Human Teeth: Explaining their Structure, Use, Formation, Growth, and Diseases, 2 parts in one, 2nd edition, 1778, half-titles, 16 copper-engraved plates, occasional light spotting and toning, library stamps, library cloth, upper joint splitting, 4to. G-M 3675-76; Norman 1116 (first editions). (1)

Hunter (John). A Treatise on the Venereal Disease, 1st edition, 1786, seven engraved plates after William Bell, burnholes in text of final index leaf, some light spotting, bound with Strictures in Vindication of Some of the Doctrines Misrepresented by Mr. Foot in his two Pamphlets Entitled, Observations upon the New Opinions of John Hunter, in his late Treatise on the Venereal Disease; Including Mr. Pott`s Plagiarisms and Misinformation on the Subject of Pus or Matter, in his Observations on that Disorder of the Corner of the Eye, Commonly Called Fistula Lachrymalis, by T. Brand, Member of the Corporation of Surgeons, London, and Surgeon Extraordinary to his Majesty`s Royal Hospital at Greenwich, 1787, 56pp., light spots, library cloth, spine a little rubbed, 4to. In Hunter`s day the venereal diseases were thought to be due to a single poison. To test this theory Hunter experimented with matter taken from a gonorrhoeal patient who, unknown to Hunter, also had syphilis. Hunter maintained that gonorrhoea and syphilis were caused by a single pathogen. Backed by the weight of his own authority, this experiment retarded the development of knowledge regarding the two diseases. Contrary to legend, however, there is no proof that Hunter actually inoculated himself with venereal disease. The hard (`Hunterian`) chancre eponymizes Hunter. This work also makes a major contribution to urological surgery` (G-M 2377). The book was the first to be published from Hunter`s private press at his house on Castle Street, established to prevent unauthorised editions of his works. This book is one of 1000 copies printed. Norman 1117. (1)

Hunter (John). Observations on Certain Parts of the Animal Oeconomy, 2nd edition, 1792, nineteen engraved plates, lacking first blank (A1), first few leaves and plates foxed, title and plates with small library stamp, final (index) leaf with small nick in upper blank margin, endpapers renewed, BMI book ticket on front pastedown, modern quarter morocco, 4to. See Norman 1118 for the first edition. (1)